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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA2
All Species:
16.36
Human Site:
S280
Identified Species:
30
UniProt:
Q9BZC7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZC7
NP_001597
2435
269873
S280
A
A
R
A
R
R
F
S
G
L
S
A
E
L
R
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
G245
L
F
L
I
K
N
I
G
L
S
D
S
V
V
Y
Rhesus Macaque
Macaca mulatta
XP_001117819
2476
273629
S307
A
A
R
A
K
R
F
S
G
L
A
D
E
L
R
Dog
Lupus familis
XP_537788
2395
264756
S280
T
A
R
A
Q
R
F
S
G
L
A
A
E
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
P41234
2434
270490
S280
T
A
R
A
Q
R
F
S
D
L
A
A
E
L
R
Rat
Rattus norvegicus
Q9ESR9
2434
270910
S280
T
A
R
A
Q
H
F
S
D
L
A
T
E
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
P223
E
S
I
I
C
A
L
P
K
E
N
L
E
A
A
Chicken
Gallus gallus
XP_422330
2276
256293
S233
H
K
A
M
C
A
L
S
Q
E
G
L
Q
R
V
Frog
Xenopus laevis
NP_001089022
2363
267334
A246
R
I
E
D
V
L
Y
A
S
I
D
F
F
K
L
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
D225
I
I
C
Q
S
P
A
D
W
L
N
N
A
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
Sea Urchin
Strong. purpuratus
XP_798273
1913
213253
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
96
82.2
N.A.
91
92.9
N.A.
39.1
35.7
36.5
37.7
N.A.
N.A.
N.A.
23.7
41.7
Protein Similarity:
100
52
96.6
86.1
N.A.
93.2
94.9
N.A.
55.7
53.5
54.7
54.5
N.A.
N.A.
N.A.
39
54.4
P-Site Identity:
100
0
80
73.3
N.A.
73.3
60
N.A.
6.6
6.6
0
6.6
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
20
93.3
93.3
N.A.
86.6
73.3
N.A.
20
13.3
20
20
N.A.
N.A.
N.A.
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
39
8
39
0
16
8
8
0
0
31
24
8
8
8
% A
% Cys:
0
0
8
0
16
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
8
16
0
16
8
0
0
0
% D
% Glu:
8
0
8
0
0
0
0
0
0
16
0
0
47
8
0
% E
% Phe:
0
8
0
0
0
0
39
0
0
0
0
8
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
24
0
8
0
0
0
0
% G
% His:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
16
8
16
0
0
8
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
0
16
0
0
0
8
0
0
0
0
8
0
% K
% Leu:
8
0
8
0
0
8
16
0
8
47
0
16
0
39
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
16
8
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
24
0
0
0
8
0
0
0
8
0
16
% Q
% Arg:
8
0
39
0
8
31
0
0
0
0
0
0
0
8
31
% R
% Ser:
0
8
0
0
8
0
0
47
8
8
8
8
0
0
0
% S
% Thr:
24
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _